How accurate are multiparametric MRI results?
Radiologist Robert Princenthal Transcript
Opening Title: How accurate are multiparametric MRI results?
How confident are we that multiparametric MR works, and I hear that particularly from urologists. They’ll have a man with an elevated PSA and they want to stick 12 needles in his gland. And we know from their own data, their cancer detection rate is only 60% and they often underestimate the aggressiveness with the Gleason score of the tumor based on the data from the TRUS biopsy.
What we found with MR data, is that a negative MR report shows and is proven to have a 95% to 97% negative predictive value. In other words if you take a man with a negative MR and he subjects himself to a biopsy anyway, you will not find significant cancer in 95% of those men. So we can help avoid men getting unnecessary benign biopsies.
Alternatively, if we call a prostate imaging positive and we see a suspicious nodule that’s one centimeter in size and aggressive, our cancer detection rate with targeted focal biopsy is over 90%. So the data is in and it clearly shows the benefit that before a man has someone stick a needle in his gland he should have a prostate MR so that he can have fewer needles and higher yield and be confident that they’ll have an accurate detection and data to help him make the best treatment decision. Or, he may find he doesn’t need a biopsy at all which is the best news possible.
Closing Title: Accuracy of diagnosis leads to better choice