What are the advantages of a “targeted” biopsy?

What are the advantages of a “targeted” biopsy?

Radiologist Robert Princenthal Transcript

Opening Title: What are the advantages of a focal targeted biopsy?

We can reduce the frequency of biopsies. Our goal together is to reduce the number of negative biopsies so we want to have fewer needles and higher yields. So for cancer detection instead of having 12 needles placed into a patient’s gland we can do a targeted biopsy with 2 needles into 1 target and confirm the diagnosis and if the rest of the gland doesn’t show any spots we can leave it alone. The negative predictive value of a normal MR is over 95% which is exceedingly high in a medical diagnostic study. Alternatively, men who are placed on active surveillance are encouraged to follow protocols which require annual repeat biopsies to try to identify if they’re progressing or not. Most men don’t tolerate that and they don’t follow the guidelines. We can do an annual MRI and prove whether the patient is staying stable or if there’s progression of disease. If we see progression of disease we can then do a focal targeted biopsy and prove progression or not… and men are so far behind the times that now we have quality prostate imaging, we have to get the word out.

Closing Title: A targeted biopsy leads to a more accurate diagnosis

Radiologist Robert Princenthal describes how a multi-parametric MRI leads to a targeted biopsy, fewer needles and more accurate diagnosis.
Robert Princenthal
Radiologist

Dr. Princenthal is a board-certified radiologist with over 25 years of expertise in diagnostic medical imaging. He has read and evaluated more than 3,000 prostate MRI studies. He attended medical school at Penn State College of Medicine. His internship was completed at Hartford Hospital in Harford, Connecticut. A diagnostic radiology residency was completed at Yale University School of Medicine at New Haven Hospital and a fellowship in interventional radiology at the University of California, San Diego. 
Video reviewed and approved by Dr. Princenthal, August 1, 2015