What are the advantages of a “targeted” biopsy?
Radiologist Robert Princenthal Transcript
Opening Title: What are the advantages of a focal targeted biopsy?
We can reduce the frequency of biopsies. Our goal together is to reduce the number of negative biopsies so we want to have fewer needles and higher yields. So for cancer detection instead of having 12 needles placed into a patient’s gland we can do a targeted biopsy with 2 needles into 1 target and confirm the diagnosis and if the rest of the gland doesn’t show any spots we can leave it alone. The negative predictive value of a normal MR is over 95% which is exceedingly high in a medical diagnostic study. Alternatively, men who are placed on active surveillance are encouraged to follow protocols which require annual repeat biopsies to try to identify if they’re progressing or not. Most men don’t tolerate that and they don’t follow the guidelines. We can do an annual MRI and prove whether the patient is staying stable or if there’s progression of disease. If we see progression of disease we can then do a focal targeted biopsy and prove progression or not… and men are so far behind the times that now we have quality prostate imaging, we have to get the word out.
Closing Title: A targeted biopsy leads to a more accurate diagnosis