What regimen did you follow for 5 years before your PCa could not be found?
Patient Dave Perez Transcript
Opening Title: Could you describe your regimen before your cancer became undetectable?
So for the first couple of years, my PSA stayed fairly stable. Then we started to see a rise, and biopsy in the towards the end of the second year, we started to find more aggressive cancer, Gleason 3 plus 4, much greater volume, and again the PSA was continuing to rise, and at that point I sought out a specialist back East who put me on some supplements, some other basic medications, like Avodart, and we saw a decline in PSA, biopsy a year after that, could no longer find any Gleason pattern 3 plus 4 all was back to 3 plus 3, and volume had decreased significantly as well.
And my PSA ultimately settled down to the low 1s, then a year ago when I took Metformin and this might have been coincidental, I don’t know, but my PSA dropped to .7 and has stayed exactly at .7 for over a year now.
The specialist I work with back East, had…and I remember him saying that, one of the things that he got wrong, was he thought that all of this excitement about Metformin that came out a few years ago and it’s possible positive impact on cancer had to be overblown, because there was just too much excitement, everyone was ascribing too much credit to the potential for Metformin. And he said now he really suspects that it does have an impact.
The regimen that I have now, for monitoring the prostate cancer is a blood test quarterly, I had been doing them monthly up until just about a year ago, but now I do quarterly blood tests, PSA, free PSA, PAP, periodically do a lipid panel, but for sure the PSA, free PSA, PAP, and DHT dihydrotestosterone every quarter. I go in for a color-Doppler trans-rectal ultrasound every six months, and I now get a multi-parametric MRI annually.
Closing Title: In December, 2014, Dave had an 18-core MRI-ultrasound fusion prostate biopsy at UCSF that did not find any cancer